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KMID : 1011620130290030241
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Korean Journal of Food and Cookey Science
2013 Volume.29 No. 3 p.241 ~ p.248
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Comparison of Antioxidant and Anti-proliferative Activities of Perilla (Perilla frutescens Britton) and Sesame (Seasamum indicum L.) leaf extracts
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곽영은:Kwak Young-Eun
기서하:Ki Seo-Ha/노은경:Noh Eun-Kyoung/신하늘:Shin Ha-Neul/한영주:Han Young-Ju/이유나:Lee Yu-Na/주지형:Ju Ji-Hyeung
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Abstract
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This study was to compare the antioxidant and anti-proliferative activities of perilla (Perilla frutescens Britton) and sesame (Seasamum indicum L.) leaf extracts. The total polyphenol levels of sesame leaf (634.7 ± 1.2 mg gallic acid equivalent/100 g dried leaf) were higher than those of perilla leaf (408.7 ± 4.6 mg gallic acid equivalent/100 g dried leaf; p<0.001). The total flavonoid levels of sesame leaf (166.7 ± 17.3 mg quercetin equivalent/100 g dried leaf) were also higher than those of perilla leaf (108.2 ± 3.7 mg quercetin equivalent/100 g dried leaf; p<0.05). ABTS radical- and DPPH radical-scavenging activities of sesame leaf extracts (78.9% and 18.2%, respectively) were higher than those of perilla leaf extracts (46.0% and 9.0%, respectively; p<0.01). Both perilla and sesame leaf extracts significantly inhibited the growth of HCT116 human colon cancer cells. However, the inhibitory activities of sesame leaf extracts were more pronounced than those of perilla leaf extracts (p<0.001). These results indicate that sesame leaf extracts have higher antioxidant and anti-proliferative activities than perilla leaf extracts. More studies are needed in order to enhance the sensory value of sesame leaf and to develop sesame leaf as health/functional food ingredients.
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KEYWORD
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Sesame leaf, perilla leaf, antioxidant activity, anti-proliferative activity, HCT116 colon cancer cell
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